FINE LINES
Early skin changes
Fine lines and subtle changes in skin quality may become more noticeable as collagen, elasticity and hydration change over time.
SKIN REJUVENATION
Rejuran skin rejuvenation.
A treatment option for patients looking to focus on skin quality rather than simply changing facial shape.
At Dermal Distinction, Rejuran is incorporated into a personalised skin consultation, with treatment considered according to your skin concerns, treatment goals and overall rejuvenation plan.
ABOUT REJURAN
Skin quality, not simply volume.
Rejuran is a polynucleotide-based injectable treatment used as part of a personalised approach to skin rejuvenation.
Rather than focusing primarily on changing facial shape or adding volume, Rejuran may be considered when the treatment goal is centred around the quality and appearance of the skin.
At Dermal Distinction, we begin by assessing your skin, the area you would like to improve and how Rejuran might fit alongside your existing skincare or treatment plan.
01
A skin-focused treatment
The emphasis is on skin quality and rejuvenation rather than simply creating additional facial volume.
02
Different areas can be considered
Depending on the formulation and your individual assessment, treatment may be considered for the face or delicate areas such as around the eyes.
03
Part of a bigger skin plan
Rejuran does not need to be considered in isolation. We can discuss how it may complement other skin treatments where appropriate.
PERSONALISED ASSESSMENT
Suitability, treatment areas and the recommended approach vary between patients. Your treatment plan is determined following consultation and assessment.
REJURAN
A skin-focused approach to facial rejuvenation.
IMMEDIATELY AFTER TREATMENT
Small raised areas can be visible at the treatment points immediately afterwards.
THE EYE AREA
Rejuran for delicate skin.
The skin around the eyes is different from the rest of the face.
It is naturally thinner and can be one of the first areas where changes in skin quality, fine lines and texture become noticeable. For some patients, Rejuran may form part of a treatment plan specifically focused on this delicate area.
During consultation we assess more than the skin directly beneath the eye. We also look at the surrounding cheek support, facial structure, pigmentation, skin quality and the nature of the concern you are hoping to improve.
01
SKIN QUALITY
Fine, delicate skin
We assess texture, fine lines and the overall quality of the skin around the eye.
02
THE UNDER-EYE
Not every shadow is the same
Under-eye concerns may relate to skin, pigmentation, contour, facial structure or a combination of factors, so assessment is important before recommending treatment.
03
WHOLE-FACE CONTEXT
We also look at the cheek
The relationship between the cheek and under-eye can influence how this area appears, which is why we do not assess the eye area in isolation.
WHAT YOU MAY NOTICE AFTERWARDS
Rejuran is placed at multiple treatment points. Small raised bumps can therefore be visible immediately after treatment, as shown in the image. We will discuss expected recovery and aftercare with you as part of your appointment.
SKIN CONCERNS
What might Rejuran be considered for?
Rejuran is generally considered when the focus of treatment is the quality and appearance of the skin.
Your consultation helps us determine what is contributing to the changes you can see and whether Rejuran is an appropriate option for that particular concern.
TEXTURE
Uneven skin texture
Rejuran may be discussed when the goal is focused on improving the overall appearance and quality of the skin rather than changing facial shape.
DELICATE SKIN
Around the eyes
The thin skin around the eyes may develop fine lines, crepey texture and other visible changes that require a different approach from the rest of the face.
SKIN QUALITY
A tired or less-refined appearance
Some patients are less concerned about a particular wrinkle and more interested in improving the overall appearance of their skin.
AGEING SKIN
Changes over time
Treatment may form part of a broader rejuvenation plan where age-related changes in skin quality are becoming more noticeable.
COMBINATION CARE
Part of a wider skin plan
Where appropriate, Rejuran may also be considered alongside other treatments when different aspects of skin ageing need to be addressed.
NOT EVERY SKIN CONCERN IS THE SAME
Fine lines, shadows, pigmentation, volume change and skin texture can look similar but have different causes. Assessment helps us determine what is actually contributing to your concern before recommending a treatment.
PN & PDRN
The science behind Rejuran.
Rejuran takes a different approach to treatments that are primarily designed to change facial volume or shape.
BOOK A CONSULTATIONRejuran is made with PN — polynucleotides, derived from highly purified salmon DNA.
Polynucleotides are long chains of DNA fragments. With Rejuran, PN is placed within the skin so that the treatment is focused on the skin environment itself rather than simply creating additional facial volume.
WHY WOULD YOU WANT PN IN THE SKIN?
To focus on the quality of the skin.
As skin ages, changes in elasticity, texture and the way the tissue repairs itself can contribute to fine lines and a less resilient appearance.
Rejuran uses PN as part of an approach aimed at improving the skin environment, supporting elasticity and improving the appearance of facial wrinkles.
01
Skin quality
The emphasis is on the condition and appearance of the skin rather than simply adding volume.
02
Elasticity
PN-based treatment may be considered where changes in skin elasticity and resilience are part of the concern.
03
Fine lines & wrinkles
Rejuran may be considered as part of a skin-focused approach to the appearance of facial wrinkles and fine lines.
AND WHAT IS PDRN?
You may also see the term PDRN, or polydeoxyribonucleotide, when reading about PharmaResearch's DNA-based technology.
PN and PDRN are related DNA-derived materials, but they are not interchangeable terms. Rejuran itself uses PN, processed using PharmaResearch's proprietary DNA Optimizing Technology (DOT™).
In simple terms:
Rejuran uses PN to focus on the skin itself — its quality,
elasticity and the appearance of fine lines — rather than
simply adding facial volume.
YOUR APPOINTMENT
What to expect from Rejuran.
Rejuran treatment involves a series of small treatment points placed across the area being addressed.
Your appointment begins with assessment and treatment planning. The treatment area, technique and approach are then tailored according to your skin, the area being treated and your individual goals.
Because Rejuran is placed at multiple points, small raised bumps can be visible immediately afterwards. We will explain what to expect and provide aftercare advice before you leave.
PLAN AROUND YOUR SCHEDULE
Temporary redness, swelling or visible treatment points may occur after treatment. Recovery varies between patients and between treatment areas, so we recommend discussing timing with us if you have an important event coming up.
CONSULT
We assess your skin.
We begin by discussing your concerns and assessing the skin and treatment area to determine whether Rejuran is appropriate for you.
PLAN
Your treatment is individualised.
The area treated and the treatment approach are planned according to your skin, anatomy and the changes you are hoping to address.
TREAT
Multiple small treatment points.
Rejuran is placed using a series of small treatment points across the selected area rather than being concentrated into one single location.
AFTERWARDS
Expect some visible treatment points.
Small raised bumps, redness or swelling can be visible immediately after treatment. We will talk you through expected recovery and your individual aftercare.
YOUR CLINICAL TEAM
Treatment begins with individual assessment.
At Dermal Distinction, your concerns, facial anatomy, medical history and treatment goals are considered before suitable options are discussed.
DR GIULIA D'ANNA
Founder · Dermal Distinction
MEET OUR TEAM
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